Search results for "Vascular Surgery"

showing 10 items of 91 documents

Efficacy of interleukin 10 gene hydrofection in pig liver vascular isolated ‘in vivo’ by surgical procedure with interest in liver transplantation

2019

AIM Liver transplantation is the only curative strategy for final stage liver diseases. Despite the great advances achieved during the last 20 years, the recipient immune response after transplantation is not entirely controlled. This results in high rates of acute cell rejection and, approximately, 10% of early mortality. Therapeutic treatment could be improved by efficiently transfecting genes that encode natural immunosuppressant proteins, employing safe procedures that could be transferred to clinical setting. In this sense, interleukin 10 plays a central role in immune tolerance response by acting at different levels. METHODS hIL10 gene was hydrofected by retrograde hydrodynamic inject…

0301 basic medicineGraft RejectionCardiovascular ProceduresSwinePhysiologymedicine.medical_treatmentGene TransferVascular SurgeryLiver transplantationPharmacologyImmune tolerance0302 clinical medicineImmune PhysiologyMedicine and Health SciencesMammalsInnate Immune SystemMultidisciplinaryQRGene Transfer TechniquesEukaryotaBlood proteinsRecombinant ProteinsInterleukin-10Interleukin 10LiverVertebratesModels AnimalMedicineCytokines030211 gastroenterology & hepatologyFemaleAnatomyResearch ArticlePlasmidsScienceImmunologyGenetic VectorsSurgical and Invasive Medical ProceduresResearch and Analysis MethodsInjectionsEnd Stage Liver Disease03 medical and health sciencesDigestive System ProceduresGene DeliveryImmune systemIn vivomedicineGene Expression and Vector TechniquesGeneticsImmune ToleranceAnimalsHumansMolecular Biology TechniquesMolecular BiologyTransplantationMolecular Biology Assays and Analysis Techniquesbusiness.industryOrganismsBiology and Life SciencesOrgan TransplantationGenetic TherapyMolecular DevelopmentLiver TransplantationTransplantation030104 developmental biologyImmune SystemAmniotesHydrodynamicsLiver functionbusinessDevelopmental BiologyPLoS ONE
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Endoscopic subfascial sectioning of incompetent perforating veins in treatment of primary varicosis

1992

Subfascial elimination of incompetent perforating veins is the most effective therapeutic principle in the treatment of trophic skin disorders associated with varicosis. A recently developed endoscopic technique allows accurate sectioning of perforating veins with direct observation of the veins and minor trauma. From November 1986 to July 1991 endoscopic sectioning of perforating veins was performed in 72 patients (103 legs). The most frequently transected perforating veins were Cockett's veins (n = 219), 24 cm perforating veins (n = 83), and Boyd's perforating veins (n = 82). Postoperative delayed wound healing was observed in 3 (2.9%) legs with pronounced trophic skin disorders in the lo…

AdultMalemedicine.medical_specialtySural nervePerforator veinVaricose VeinsPostoperative ComplicationsmedicineHumansAgedAged 80 and overDysesthesiaVarixRupture Spontaneousbusiness.industryEndoscopyAnatomyMiddle AgedVascular surgeryFasciotomySurgerySaphenous nerveVenous InsufficiencyFemaleSurgerymedicine.symptomVaricesbusinessVascular Surgical ProceduresFollow-Up StudiesAbdominal surgeryWorld Journal of Surgery
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A Single-Center Experience with Lung Transplants During the COVID-19 Pandemic

2021

BACKGROUND This single-center study analyzed distinctions between lung transplants performed in the Department of Cardiac and Vascular surgery of the University Clinical Center in Gdansk, Poland before and during the COVID-19 pandemic. MATERIAL AND METHODS There were 189 patients who underwent the qualification procedure to lung transplantation in the Department of Cardiac and Vascular Surgery of the University Clinical Center in Gdansk, Poland in the years 2019 and 2020. The control group consisted of 12 patients transplanted in 2019, and the study group consisted of 16 patients transplanted in 2020. RESULTS During 2019, the qualification process was performed in 102 patients with pulmonar…

AdultMalemedicine.medical_specialtyTissue and Organ ProcurementCoronavirus disease 2019 (COVID-19)Waiting Listsmedicine.medical_treatmentSingle CenterHealth Services AccessibilityPandemicmedicineLung transplantationHumansPandemicsAgedTransplantationLung transplantsOriginal PaperGeographic areabusiness.industryMortality rateGeneral surgeryCOVID-19General MedicineVascular surgeryMiddle AgedOutcome and Process Assessment Health CareFemalePolandbusinessFollow-Up StudiesLung TransplantationAnnals of Transplantation
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Factors Influencing Morbidity and Mortality after Pancreaticoduodenectomy: Critical Analysis of 221 Resections

1999

A critical analysis of morbidity and mortality for pancreatico-duodenectomy was performed on 221 patients. During the 1960s and 1970s, the morbidity and mortality for pancreaticoduodenectomy were so high that many thought the operative procedure ought to be abandoned. During the 1980s, however, many centers reported mortality rates around 5% and a morbidity of 25% to 35%. Others still reported a mortality of more than 10% and a morbidity of up to 65%. The reasons for these discrepancies are of major interest. In a prospective case-control study 760 patients with malignant and benign diseases of the pancreas were treated in our hospital between September 1, 1985 and April 30, 1997. In 221 ca…

AdultMalemedicine.medical_specialtymedicine.medical_treatmentBlood Loss SurgicalPancreaticoduodenectomyPostoperative ComplicationsmedicineHumansProspective StudiesSurvival rateAgedAged 80 and overPancreatic ductPortal Veinbusiness.industryPatient SelectionGeneral surgeryMortality ratePancreatic DuctsPancreatic DiseasesBilirubinMiddle AgedVascular surgeryPancreaticoduodenectomyCardiac surgerySurgeryPancreatic NeoplasmsSurvival Ratemedicine.anatomical_structureCardiothoracic surgeryCase-Control StudiesRegression AnalysisFemaleSurgeryClinical CompetencebusinessFollow-Up StudiesAbdominal surgeryWorld Journal of Surgery
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Pharmacological thrombolysis: one more weapon for free-flap salvage.

2005

Despite the high success rate of free-tissue transfer, thrombosis still complicates 5-30% of cases. Meticoulous technique, careful vessel selection, and pharmacological prophylaxis are not always enough to avoid thrombosis. Early diagnosis and reintervention provide the only way to salvage a thrombosed free flap, in case of either arterial or venous thrombosis. When kinking, torsion, or external compression of the pedicle are ruled out, and thrombectomy and redo of the anastomosis are unsuccessful, the last resort to save the flap is thrombolytic therapy. The authors present their experience with the salvage of two otherwise lost flaps by means of urokinase thrombolysis through direct intra…

AdultMalemedicine.medical_specialtymedicine.medical_treatmentFree flapAnastomosisTHERAPYSurgical FlapsMICROVASCULAR SURGERYFibrinolysismedicineMANAGEMENTHumansThrombolytic TherapyVeinUrokinaseAged 80 and overVenous Thrombosisbusiness.industrySTREPTOKINASE SALVAGEGraft SurvivalThrombolysisTHROMBECTOMYmedicine.diseaseThrombosisUrokinase-Type Plasminogen ActivatorSurgeryVenous thrombosismedicine.anatomical_structureSurgerybusinessmedicine.drugMicrosurgery
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The role of noninvasive brain oximetry in adult critically ill patients without primary non-anoxic brain injury.

2021

A primary objective in intensive care and perioperative settings is to promote an adequate supply and delivery of oxygen to tissues and organs, particularly to the brain. Cerebral near infrared spectroscopy (NIRS) is a noninvasive, continuous monitoring technique, that can be used to assess cerebral oxygenation. Using NIRS to monitor cerebral oximetry is not new and has been in widespread use in neonates and cardiac surgery for decades. In addition, it has become common to see NIRS being used in adult and pediatric cardiac surgery, acute neurological diseases, neurosurgical procedures, vascular surgery, severe trauma and other acute medical diseases. Furthermore, recent evidence suggests a …

Adultmedicine.medical_specialtyCritically illbusiness.industrymedicine.medical_treatmentCritical IllnessInfant NewbornBrainPerioperativeLiver transplantationVascular surgeryCardiac surgeryOxygenAnesthesiology and Pain MedicineIntensive careBrain InjuriesCerebrovascular CirculationOrthopedic surgerymedicineHumansOximetryIntensive care medicinebusinessChildAnoxic brain injuryMinerva anestesiologica
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Tuberculous aortitis in an human immunodeficiency virus-positive Ivorian migrant: A case report.

2021

We report an unusual case of a 35-year-old Ivorian migrant with an abdominal mass and medical history relevant for human immunodeficiency virus-2 positivity with a CD4/CD8 ratio of 0.63; Mantoux and lymphocyte stimulation tests (QuantiFERON) were positive. 3D-CT images revealed a voluminous non-homogeneous retroperitoneal mass in the right abdominal region presenting no significant contrast impregnation. Thoraco-abdominal aorta presented diffuse-altered morphology with multiple ectasias throughout its course and an aneurysm at the level of the subrenal tract. The patient underwent vascular surgery. Mycobacterium tuberculosis complex was detected by polymerase chain reaction performed on in…

Adultmedicine.medical_specialtyDermatologyQuantiFERONAneurysmTuberculous aortitisEctasiamedicinecase reportHumansTuberculosisPharmacology (medical)Medical history3D reconstructionextrapulmonary tuberculosiAortitisTransients and MigrantsbiologyAortitisbusiness.industryhuman immunodeficiency viruPublic Health Environmental and Occupational HealthHIVVascular surgerymedicine.diseasebiology.organism_classificationAbdominal massInfectious DiseasesCote d'IvoireMycobacterium tuberculosis complexRadiologymedicine.symptombusinessInternational journal of STDAIDS
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Early results of a low-profile stent-graft for thoracic endovascular aortic repair

2020

Purpose To assess outcomes of a low-profile thoracic stent-graft in the treatment of thoracic aortic pathologies. Methods A retrospective analysis of all consecutive patients with aortic thoracic pathologies treated with the RelayPro device in two university hospitals between October 2018 and July 2019. Results 23 patients (65% men; mean age 63.4 ± 15 years) were treated. Pathologies included aortic dissections (n = 10), 5 residual type A (22%) and 5 type B (22%), 6 degenerative aortic aneurysms (26%), 4 penetrating aortic ulcers (17%), and aortic erosion, intramural hematoma and aortic rupture (n = 1 and 4% in each case). Two cases (9%) were emergent and two urgent. Proximal landing was a…

Aortic archElephant trunksEndoleakCardiovascular ProceduresPhysiologymedicine.medical_treatmentVascular SurgeryAorta ThoracicPathology and Laboratory MedicineNervous SystemPostoperative ComplicationsMedicine and Health SciencesLeukocytosisAortaCerebrospinal FluidAged 80 and overMultidisciplinaryQRArteriesMiddle AgedBody FluidsTreatment OutcomeMedicineEngineering and TechnologyFemaleStentsmedicine.symptomAnatomyResearch ArticleBiotechnologymedicine.medical_specialtyScienceAortic DiseasesBioengineeringSurgical and Invasive Medical ProceduresBlood Vessel Prosthesis Implantationmedicine.arterymedicineHumansAortic ruptureAgedRetrospective StudiesAortabusiness.industryStentBiology and Life SciencesVascular surgerySurgeryAppositionSurgical RepairAnatomical PathologyCardiovascular AnatomyBlood VesselsMedical Devices and EquipmentbusinessPLoS ONE
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Congenital mitral regurgitation caused by a perforation in the anterior leaflet: Perioperative evaluation by color-coded Doppler echocardiography

1990

Color-coded two-dimensional (2D) echocardiography confirmed the presence of severe congenital mitral regurgitation in an 8-month-old infant. Intraoperative inspection revealed an isolated perforation in the anterior leaflet.

Congenital mitral regurgitationmedicine.medical_specialtyPerforation (oil well)Doppler echocardiographyInternal medicinemedicineHumanscardiovascular diseasesMitral regurgitationAnterior leafletmedicine.diagnostic_testbusiness.industryInfantMitral Valve InsufficiencyPerioperativeVascular surgeryEchocardiography DopplerCardiac surgerySurgeryPediatrics Perinatology and Child Healthcardiovascular systemCardiologyMitral ValveFemaleCardiology and Cardiovascular MedicinebusinessPediatric Cardiology
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Relative incidence and mortality of congenital heart defects diagnosed by angiohemodynamic methods: a 17-year study.

1992

Over a 17-year period (January 1971 to January 1988), 2322 children, aged 0-14 years, were diagnosed as having congenital heart disease (CHD) by cardiac catheterization and angiography. Excluding those with highly complex or undiagnosed defects, there were 2156 children with CHD, 72.4% of whom were treated surgically, with a total surgical mortality rate of 24.1%. After a mean follow-up of 9 years the overall mortality of the cohort was 29.9%, 29.1% occurring in the first month of life, 39.6% between 1 month and 1 year, and 31.2% between 1 and 14 years. The incidence, mortality, and age at death of each cardiac defect are presented and compared with the results of other studies. The overall…

Cross-Cultural ComparisonHeart Defects CongenitalMalePediatricsmedicine.medical_specialtyCardiac CatheterizationHeart diseaseAdolescentRelative incidencemedicine.medical_treatmentCohort StudiesPostoperative ComplicationsmedicineHumansChildCardiac catheterizationmedicine.diagnostic_testbusiness.industryIncidence (epidemiology)AngiocardiographyPalliative CareHemodynamicsInfant NewbornInfantVascular surgerymedicine.diseaseCardiac surgerySurvival RateSpainChild PreschoolPediatrics Perinatology and Child HealthCohortAngiographyFemaleCardiology and Cardiovascular MedicinebusinessFollow-Up StudiesPediatric cardiology
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